GLP-1 Weight Loss Calculator
Semaglutide (Wegovy/Ozempic)
Projected weight loss on semaglutide based on STEP trial data
lbs
Tirzepatide (Mounjaro/Zepbound)
Projected weight loss on tirzepatide based on SURMOUNT trial data
lbs
Formula
Estimated Loss = Current Weight x Max Loss% x Progress Factor | Progress Factor = ln(1 + months/6) / ln(1 + 18/6)
Frequently Asked Questions
How much weight can you lose on GLP-1 medications?
Clinical trials show average weight loss of 15% body weight on semaglutide (Wegovy) and up to 20.9% on tirzepatide (Zepbound) over 68-72 weeks. Results vary widely -- some patients lose more, others less. Factors include diet, exercise, starting weight, and individual biology.
When do you start losing weight on semaglutide or tirzepatide?
Most patients begin losing weight within the first 4 weeks, though the dose is gradually increased over 16-20 weeks. The fastest weight loss typically occurs between months 3 and 9. Weight loss generally plateaus around 12-18 months.
Is weight loss on GLP-1 medications permanent?
Studies show that most patients regain approximately two-thirds of lost weight within one year of stopping GLP-1 medications. Maintaining weight loss typically requires ongoing treatment, lifestyle changes, or both. Discuss long-term plans with your doctor.
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