Opioid Equianalgesic Calculator
Opioid Equianalgesic Conversion
Formula
Equivalent Dose = (Current Dose x From MME Factor) / To MME Factor | Reduce by 25-50% for rotation
Frequently Asked Questions
What is equianalgesic dosing?
Equianalgesic dosing compares doses of different opioids that provide approximately equal pain relief. 30 mg oral morphine is the standard reference dose.
Why reduce dose when switching opioids?
A 25-50% dose reduction is recommended when rotating opioids due to incomplete cross-tolerance. Patients may be more sensitive to the new opioid.
What are morphine milligram equivalents (MME)?
MME standardize opioid doses to oral morphine equivalents. CDC guidelines flag prescriptions >= 50 MME/day as higher risk and >= 90 MME/day as warranting careful justification.
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